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Multiplicity-edited broadband HMBC NMR spectra.

Nyberg NT, Sørensen OW

Carlsberg Laboratory, Gamle Carlsberg Vej 10, DK-2500 Valby, Denmark.

A new, edited HMBC experiment is introduced that leads to two subspectra according to the number of protons attached to 13C nuclei being even or odd, i.e. one subspectrum with C + CH2 and another with CH + CH3. This experiment can be useful for resolving spectral overlap among the typically large number of peaks in HMBC spectra. It is implemented in a broadband version similar to broadband HMBC and demonstrated on prednisolone [(11beta)-11,17,21-trihydroxypregna-1,4-diene-3,20-dione].

Published 15 March 2006 in Magn Reson Chem, 44(4): 451-4.
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